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Zidovudine (AZT) 300 mg Tab + Lamivudine (3TC) 150 mg Tab (Combivir)
Trade Name
Prescriber Category
:
:
Combivir
A/KK
Department
Antimicrobial Restriction
:
:
ID
N/A
INDICATION (BLUE BOOK / UKK)
Management of HIV infected adults and children more than 12 years of age with progressive immunodeficiency in combination with at least one other antiretroviral drug
DOSING FOR ADULTS GUIDE [DIAMS HSgB]
AZT 300 mg/ 3TC 150mg (1 tablet) PO q12h
RENAL DOSE ADJUSTMENT IN ADULTS GUIDE [DIAMS HSgB]
CrCl <50 ml/min:
Co-formulated tablet is not recommended in CrCl <50 ml/min.
CrCl <50 ml/min requires renal dosage adjustment for Lamivudine (3TC). Change Zidovudine (AZT) to alternative agent as AZT as a single agent has been phased out.
IV TO PO GUIDE [DIAMS HSgB]
N/A
EXTENDED INFUSION GUIDE [DIAMS HSgB]
In-progress
SPECIAL MONITORING & PRECAUTION GUIDE [DIAMS HSgB]
In-progress
ALTERNATIVE DOSING (BLUE BOOK / HSgB DRUG LIST)
ADULT and CHILD over 12 years: 1 tablet bd
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