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Tenofovir Disoproxil Fumarate 300mg & Emtricitabine 200mg Tab

Trade Name

Prescriber Category

:

:

Tenvir EM

A/KK

Department

Antimicrobial Restriction

:

:

ID

N/A

INDICATION (BLUE BOOK / UKK)

In combination with other antiretroviral agents (such as non-nucleoside reverse transcriptase inhibitors or protease inhibitors) for the treatment of HIV-1 infected in adults.

DOSING FOR ADULTS GUIDE [DIAMS HSgB]

TDF 300 mg / FTC 200 mg (1 tablet) PO q 24h

RENAL DOSE ADJUSTMENT IN ADULTS GUIDE [DIAMS HSgB]

30-49 ml/min:
1 tablet PO q48h
Monitor for worsening renal function / consider switching to TAF/FTC for pts with HBV co-infection

<30 ml/min or HD:
co-formulated tablet is not recommended.

Consider switching TDF to TAF for pts with HBV co-infection

Use single formulation of each drug:
Tenofovir alafenamide (TAF) & Lamivudine (3TC)** and adjust according to individual renal dose. [**Use 3TC as alternative to FTC as FTC single agent not available in HSgB]

IV TO PO GUIDE [DIAMS HSgB]

N/A

EXTENDED INFUSION GUIDE [DIAMS HSgB]

In-progress

SPECIAL MONITORING & PRECAUTION GUIDE [DIAMS HSgB]

In-progress

ALTERNATIVE DOSING (BLUE BOOK / HSgB DRUG LIST)

1 tablet once daily.

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