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Sulfadoxine 500 mg + Pyrimethamine 25 mg Tab

Trade Name

Prescriber Category

:

:

Fansidar

B

Department

Antimicrobial Restriction

:

:

N/A

INDICATION (BLUE BOOK / UKK)

Treatment of Plasmodium falciparum malaria in patients in whom chloroquine resistance is suspected; malaria prophylaxis for travellers to areas where chloroquine-resistant malaria is endemic.

DOSING FOR ADULTS GUIDE [DIAMS HSgB]

N/A

RENAL DOSE ADJUSTMENT IN ADULTS GUIDE [DIAMS HSgB]

N/A

IV TO PO GUIDE [DIAMS HSgB]

N/A

EXTENDED INFUSION GUIDE [DIAMS HSgB]

In-progress

SPECIAL MONITORING & PRECAUTION GUIDE [DIAMS HSgB]

In-progress

ALTERNATIVE DOSING (BLUE BOOK / HSgB DRUG LIST)

Chloroquine resistant falciparum malaria acute attack Adult: Per tab contains pyrimethamine 25 mg and sulfadoxine 500 mg: 2-3 tabs as a single dose. Do not repeat for at least 7 days. Child: Pyrimethamine 25mg + Sulfadoxine 500mg (Tablet): <2 yr (5-10 kg): 1/2 (half) tab as a single dose; 2-5 yr (>10-20 kg): 1 tab as a single dose; 5-10 yr (< 20-30 kg): 1 1/2 (one and half) tab as a single dose; 10-14 yr (> 30-45 kg): 2 tab as a single dose. Do not repeat for at least 7 days. Renal impairment: Dose reduction may be needed. Severe: contra-indicated. Hepatic impairment: Dose reduction may be needed. Severe: contra-indicated.

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