Rifampicin 600 mg Inj

Trade Name

Prescriber Category

Rifadin

UKK

Department

Antimicrobial Restriction

N/A

INDICATION (BLUE BOOK / UKK)

Tuberculosis

DOSING FOR ADULTS GUIDE [DIAMS HSgB]

Mycobacterium or MRSA Infection:
10 mg/kg IV or PO q24h
(usually 600 mg IV or PO q24h)

*Round up to the nearest 150 mg
*For mRSA bacteremia, add Rifampicin after culture clearance

Prosthetic Joint Infection or Prosthetic Valve Endocarditis:
300 - 450 mg IV or PO q1h

With HIV PIs:
Not recommended - consider changing to Rifabutin

RENAL DOSE ADJUSTMENT IN ADULTS GUIDE [DIAMS HSgB]

<10 ml/min or HD:
Usual dose
Some recommend a 50% decrease in dose

IV TO PO GUIDE [DIAMS HSgB]

N/A

EXTENDED INFUSION GUIDE [DIAMS HSgB]

In-progress

SPECIAL MONITORING & PRECAUTION GUIDE [DIAMS HSgB]

In-progress

ALTERNATIVE DOSING (BLUE BOOK / HSgB DRUG LIST)

Adult : A single daily dose of 600mg given over 2-3 hours Children : Up to 20mg per kg of body weight each day. Maximum dose is 600mg each day

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