Micafungin Sodium 50mg Powder for Solution for Infusion
Trade Name
Prescriber Category
:
:
Mycamine
A*
Department
Antimicrobial Restriction
:
:
MED (ID),
ANAES/ICU
Red Category (ID/Anaes)
INDICATION (BLUE BOOK / UKK)
1) Treatment of invasive candidiasis, including candidemia in adults when intolerance or resistance to Amphotericin B or Fluconazole. * 2) Treatment of invasive candidiasis in children
DOSING FOR ADULTS GUIDE [DIAMS HSgB]
100 mg IV q24h
*Consider 150 mg IV q24h for endocarditis
RENAL DOSE ADJUSTMENT IN ADULTS GUIDE [DIAMS HSgB]
No dosage adjustment required.
IV TO PO GUIDE [DIAMS HSgB]
N/A
EXTENDED INFUSION GUIDE [DIAMS HSgB]
In-progress
SPECIAL MONITORING & PRECAUTION GUIDE [DIAMS HSgB]
In-progress
ALTERNATIVE DOSING (BLUE BOOK / HSgB DRUG LIST)
i) Dosage for adults, adolescents ≥ 16 years of age and the elderly for the treatment of invasive candidiasis: - Body weight > 40kg: 100mg/day* - Body weight ≤ 40kg: 2mg/kg/day* *If patient's response is inadequate, e.g. persistence of cultures or if clinical condition does not improve, the dose may be increased to 200 mg/day in patients weighing > 40kg or 4mg/kg/day in patients weighing ≤ 40kg. Treatment duration for invasive candidiasis: should be a minimum of 14 days. The antifungal treatment should continue for at least one week after two sequential negative blood cultures have been obtained and after resolution of clinical signs and symptoms of infection. ii) Dosage for children: - Body weight ≤ 40kg: 2mg/kg/day; - Body weight > 40kg: 100mg/day