Metronidazole 200 mg Tab
Trade Name
Prescriber Category
:
:
Flagyl
B
Department
Antimicrobial Restriction
:
:
-
Green Category
INDICATION (BLUE BOOK / UKK)
Anaerobic infections.
DOSING FOR ADULTS GUIDE [DIAMS HSgB]
Usual dose:
500 mg IV q8h
or
400 mg PO q8h
H. pylori infection, Non-gonococcal urethritis (NGU), Pelvic inflammatory disease (PID) or Bacterial vaginosis:
400 mg PO q12h
Entamoeba histolytica liver abscess:
750 mg IV q8h
or
800 mg PO q8h
RENAL DOSE ADJUSTMENT IN ADULTS GUIDE [DIAMS HSgB]
No dosage adjustment required
IV TO PO GUIDE [DIAMS HSgB]
IV Metronidazole:
500 mg q12h --> Tab Metronidazole 400 mg BD
500 mg q8h --> Tab Metronidazole 400 mg TDS
750 mg q8h --> Tab Metronidazole 800 mg TDS
Bioavailability: 100%
*Abstain from alcohol to avoid disulfiram-like reaction.
EXTENDED INFUSION GUIDE [DIAMS HSgB]
In-progress
SPECIAL MONITORING & PRECAUTION GUIDE [DIAMS HSgB]
In-progress
ALTERNATIVE DOSING (BLUE BOOK / HSgB DRUG LIST)
Anaerobic bacterial infections Adult: Initially, 800 mg followed by 400 mg 8 hly for about 7 days. Other recommended doses: 500 mg 8 hrly or 7.5 mg/kg 6 hrly (max: 4 g in 24 hr). Child: 7.5 mg/kg 8 hrly. Elderly: Use lower end of adult dose recommendations. Do not admin as a single dose. Prophylaxis of postoperative anaerobic bacterial infections Adult: 400 mg by mouth 8 hrly in the 24 hr prior to surgery followed postoperatively by IV or rectal admin until oral therapy is possible. Other sources recommend that oral doses be initiated only 2 hr prior to surgery and that number of doses for all admin routes be limited to a total of 4. Elderly: Dose reduction may be necessary. Tab: Should be taken with food.