Meropenem 500 mg Inj
Trade Name
Prescriber Category
:
:
Meronem
A*
Department
Antimicrobial Restriction
:
:
-
Yellow Category
INDICATION (BLUE BOOK / UKK)
1. Nosocomial pneumonia
2. Bacterial Meningitis
3. Empirical treatment for presume infections in patients (adult & children) with febrile neutropenia, used as monotherapy or in combination with anti-virals or antifungal agent.
4. Septicaemia
5. Urinary tract infection
6. Intra-abdominal infections
7. Gynaecological infections
DOSING FOR ADULTS GUIDE [DIAMS HSgB]
Usual dose:
1,000 mg IV q8h
Severe infections, MDR Organisms or CNS infections:
2,000 mg IV q8h
* Consider extended infusion.
* Refer to DIAMS - Extended infusion [inprogress].
RENAL DOSE ADJUSTMENT IN ADULTS GUIDE [DIAMS HSgB]
1. Original dose: 1,000 mg IV q8h
CrCl 30-50 ml/min:
1,000 mg IV q12h
CrCl 10-29 ml/min:
500 mg IV q12h
CrCl <10 ml/min or HD:
500 mg IV q24h [Administer dose after HD on dialysis days]
2. Original dose: 2,000 mg IV q8h
CrCl 30-50 ml/min:
1,000 mg IV q8h
or
2,000 mg IV q12h
CrCl 10-29 ml/min:
1,000 mg IV q12h
CrCl <10 ml/min or HD:
1,000 mg IV q24h [Administer dose after HD on dialysis days]
IV TO PO GUIDE [DIAMS HSgB]
N/A
EXTENDED INFUSION GUIDE [DIAMS HSgB]
In-progress
SPECIAL MONITORING & PRECAUTION GUIDE [DIAMS HSgB]
In-progress
ALTERNATIVE DOSING (BLUE BOOK / HSgB DRUG LIST)
ADULT: 1-2 every 8 hourly (refer to specific indication dosing)
CHILD (aged 3 months and over): 10-40mg/kg 8 hourly, if body weight over 50kg, adult dosage should be used.
Dosing is accoding to product insert / protocol