Levofloxacin 500 mg Inj.

Trade Name

Prescriber Category

Department

Antimicrobial Restriction

Red Category (ID)

INDICATION (BLUE BOOK / UKK)

Community Acquired Pneumonia

DOSING FOR ADULTS GUIDE [DIAMS HSgB]

Low dose:
500 mg IV or PO q24h

High dose:
750-1,000 mg IV or PO q24h

RENAL DOSE ADJUSTMENT IN ADULTS GUIDE [DIAMS HSgB]

CrCl 20-49 ml/min:
Low Dose:
500 mg once, then 250 mg q24h, IV or PO
or
500 mg q48h, IV or PO

High Dose:
750 mg q48h, IV or PO

CrCl <20 ml/min or HD:
Low Dose:
500 mg once, then 250 mg q48h, IV or PO

High Dose:
750 mg once, then 500 mg q48h, IV or PO
[Administer dose after HD on dialysis days]

IV TO PO GUIDE [DIAMS HSgB]

IV Levofloxacin:
500 mg q24h --> Tab Levofloxacin 500 mg OD
750 mg q24h --> Tab Levofloxacin 750 mg OD

Bioavailability:~99%

*Hold tue feeds 1H before & 2H after Levofloxacin given

EXTENDED INFUSION GUIDE [DIAMS HSgB]

In-progress

SPECIAL MONITORING & PRECAUTION GUIDE [DIAMS HSgB]

In-progress

ALTERNATIVE DOSING (BLUE BOOK / HSgB DRUG LIST)

500 mg daily for 7 - 14 days

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