Itraconazole 100 mg Cap
Trade Name
Prescriber Category
:
:
Sporanox
A/KK
Department
Antimicrobial Restriction
:
:
-
Yellow Category
INDICATION (BLUE BOOK / UKK)
i) Dermatomycosis including pityriasis versicolor ii) Oral candidiasis iii) Palmar tinea manus and plantar tinea pedis iv) Fingernail onychomycosis v) Toenail onychomycosis vi) Vulvovaginal candidiasis
DOSING FOR ADULTS GUIDE [DIAMS HSgB]
Usual dose:
100-200 mg PO q12h
Consolidation therapy for cryptococcal meningitis, histoplasmosis or penicilliosis:
200 mg PO q8h for 3 days,
followed by 200 mg PO q12h
Maintenance therapy / secondary prophylaxis for cryptococcal meningitis / histoplasmosis / penicilliosis:
200 mg PO q24h
Treatment of Oropharyngeal candidiasis (oral thrush) / Oesophageal candidiasis:
200 mg PO q24h
Pulse regimen for Onychomycoses:
200 mg PO q12h x 1 week per month
RENAL DOSE ADJUSTMENT IN ADULTS GUIDE [DIAMS HSgB]
CrCl <10 ml/min:
50% of normal dose PO q12h
HD:
100 mg PO q12-24h
[No significant itraconazole removal during HD]
IV TO PO GUIDE [DIAMS HSgB]
N/A
EXTENDED INFUSION GUIDE [DIAMS HSgB]
In-progress
SPECIAL MONITORING & PRECAUTION GUIDE [DIAMS HSgB]
In-progress
ALTERNATIVE DOSING (BLUE BOOK / HSgB DRUG LIST)
i) 200 mg once daily for 7 days ii) 100 mg daily for 15 days iii) 200 mg twice daily for 7 days iv) 200mg twice daily for 1 week per month for 2 months v) 200 mg twice daily for 1 week per month for 3 months vi)200 mg morning and evening for 1 day or 200 mg once daily for 3 days