Ganciclovir Sodium 546 mg/10 ml Inj
Trade Name
Prescriber Category
:
:
Cymevene
A*
Department
Antimicrobial Restriction
:
:
ID
Red Category (ID)
INDICATION (BLUE BOOK / UKK)
Treatment of cytomegalovirus (CMV) disease in immunocompromised patients, prevention of CMV disease during immunosuppressive therapy following organ transplantation
DOSING FOR ADULTS GUIDE [DIAMS HSgB]
CMV Induction Therapy:
5 mg/kg IV q12h
CMV Maintenance Therapy:
5 mg/kg IV q24h
RENAL DOSE ADJUSTMENT IN ADULTS GUIDE [DIAMS HSgB]
1. CMV Induction Therapy:
CrCl 50-69 ml/min:
2.5 mg/kg IV q12h
CrCl 25-49 ml/min:
2.5 mg/kg IV q24h
CrCl 10-24 ml/min:
1.25 mg/kg IV q24h
CrCl <10 ml/min or HD:
1.25 mg/kg IV three times per week
[Administer dose after HD on day of dialysis]
2. CMV Maintenance Therapy:
CrCl 50-69 ml/min:
2.5 mg/kg IV q24h
CrCl 25-49 ml/min:
1.25 mg/kg IV q24h
CrCl 10-24 ml/min:
0.625 mg/kg IV q24h
CrCl <10 ml/min or HD:
0.625 mg/kg IV three times per week
[Administer dose after HD on day of dialysis]
IV TO PO GUIDE [DIAMS HSgB]
N/A
EXTENDED INFUSION GUIDE [DIAMS HSgB]
In-progress
SPECIAL MONITORING & PRECAUTION GUIDE [DIAMS HSgB]
In-progress
ALTERNATIVE DOSING (BLUE BOOK / HSgB DRUG LIST)
Initial: 5 mg/kg infused over 1 hour 12 hourly for 14 - 21 days (CMV retinitis treatment) or 7 - 14 days (CMV disease prevention). Long term maintenance: 6 mg/kg daily for 5 days/week or 5 mg/kg daily for 7 days/week