Cloxacillin Sod 500 mg Inj
Trade Name
Prescriber Category
:
:
Orbenin
B
Department
Antimicrobial Restriction
:
:
-
Green Category
INDICATION (BLUE BOOK / UKK)
Treatment of susceptible bacterial infections, notably penicillinase-producing staphylococci infections
DOSING FOR ADULTS GUIDE [DIAMS HSgB]
Usual dose:
2 gm IV IV q4-6h
MSSA Bacteremia / Endocarditis / CNS Infections / Obese patients:
2 gm IV q4h
Cellulitis or other soft tissue infection (SSTI):
1-2 gm IV q4-6h
RENAL DOSE ADJUSTMENT IN ADULTS GUIDE [DIAMS HSgB]
No dosage adjustment required.
IV TO PO GUIDE [DIAMS HSgB]
IV Cloxacillin:
500 mg q6h --> Cap Claxacillin 250 mg QID
1,000 mg q6h --> Cap Cloxacillin 500 mg QID
2,000 mg q6h --> *Cap Cloxacillin 1000 mg QID
* May increase oral dose for serious infections
(max dose: 6,000 mg/day)
Bioavailability: ~50%
* Oral dose of 250 mg for mild infections
EXTENDED INFUSION GUIDE [DIAMS HSgB]
In-progress
SPECIAL MONITORING & PRECAUTION GUIDE [DIAMS HSgB]
In-progress
ALTERNATIVE DOSING (BLUE BOOK / HSgB DRUG LIST)
HSgB Practice
CHILD : 25-50 mg/kg/DOSE every 6 hourly
ADULT: 250 to 500 mg every 6 hours depending on type and severity of infection. CHILD less than 20 kg: 25 to 50 mg/kg/day in equally divided doses every 6 hours