Caspofungin Acetate (50 mg & 70 mg Inj)
Trade Name
Prescriber Category
:
:
Cancidas
A*
Department
Antimicrobial Restriction
:
:
ID (halt purchase)
Red Category (ID)
INDICATION (BLUE BOOK / UKK)
i) Confirmed systemic fungal infection in patients who are refractory or intolerant to other fungal therapies.
ii) For pediatric patient (12 month and older) for the following indications:
a) Empirical therapy for presumed fungal infections in febrile, neutropenic patients
b) Treatment of invasive candidiasis, including candidemia and the following Candida infections ; intra-abdominal abscesses, peritonitis and pleural space infections
c) Treatment of esophageal candidiasis
d) Treatment of invasive Aspergillosis in patients who are refractory to or intolerant of others therapy (eg : Amphotericin B)
DOSING FOR ADULTS GUIDE [DIAMS HSgB]
N/A
RENAL DOSE ADJUSTMENT IN ADULTS GUIDE [DIAMS HSgB]
N/A
IV TO PO GUIDE [DIAMS HSgB]
N/A
EXTENDED INFUSION GUIDE [DIAMS HSgB]
In-progress
SPECIAL MONITORING & PRECAUTION GUIDE [DIAMS HSgB]
In-progress
ALTERNATIVE DOSING (BLUE BOOK / HSgB DRUG LIST)
i) Invasive aspergillosis & invasive candidiasis:
ADULT:
Initially, 70 mg infused over 1 hour followed by subsequent doses of 50 mg/day.
(i) Oesophageal candidiasis:
ADULT:
50 mg by slow IV infusion over approximately 1 hour
ii) For all indications, a loading dose of 70 mg/m2 on D1 followed by maintenance dose of 50 mg/m2 od.