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Amoxycillin + Clavulanic Acid 1.2 g Inj

Trade Name

Prescriber Category

:

:

Augmentin

A

Department

Antimicrobial Restriction

:

:

-

Green Category

INDICATION (BLUE BOOK / UKK)

Infections caused by susceptible organisms. Respiratory tract, skin, soft tissue, GUT infection, septicaemia, peritonitis, post-operative infection & osteomyelitis

DOSING FOR ADULTS GUIDE [DIAMS HSgB]

Usual dose:
1,200 mg IV q8h

Serious infections, Liver abscess, Lung abscess or Empyema:
1,200 mg IV q6-8h

RENAL DOSE ADJUSTMENT IN ADULTS GUIDE [DIAMS HSgB]

CrCl 30-50 ml/min:
1,200 mg IV q8h

CrCl 10-29 ml/min:
1,200 mg IV q12h

CrCl < 10 ml/min or HD:
1,200 mg IV q24h
[Administer dose after HD on dialysis day]

IV TO PO GUIDE [DIAMS HSgB]

IV Amoxycillin/Clavulanic Acid 1.2 g q8h
--> Tab Amoxicillin/ Clavulanate 625 mg TDS

Bioavailability:
Amoxicillin: 80%
Clavulanate: 30-98%

EXTENDED INFUSION GUIDE [DIAMS HSgB]

In-progress

SPECIAL MONITORING & PRECAUTION GUIDE [DIAMS HSgB]

In-progress

ALTERNATIVE DOSING (BLUE BOOK / HSgB DRUG LIST)

CHILD
less than 3 months: 30 mg/kg 12 hourly.
3 months - 12 years: 30 mg/kg 6 - 8 hourly.

ADULT:
1.2 g by IV or intermittent infusion 6 - 8 hourly

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