


Amoxycillin + Clavulanic Acid 1.2 g Inj
Trade Name
Prescriber Category
:
:
Augmentin
A
Department
Antimicrobial Restriction
:
:
-
Green Category
INDICATION (BLUE BOOK / UKK)
Infections caused by susceptible organisms. Respiratory tract, skin, soft tissue, GUT infection, septicaemia, peritonitis, post-operative infection & osteomyelitis
DOSING FOR ADULTS GUIDE [DIAMS HSgB]
Usual dose:
1,200 mg IV q8h
Serious infections, Liver abscess, Lung abscess or Empyema:
1,200 mg IV q6-8h
RENAL DOSE ADJUSTMENT IN ADULTS GUIDE [DIAMS HSgB]
CrCl 30-50 ml/min:
1,200 mg IV q8h
CrCl 10-29 ml/min:
1,200 mg IV q12h
CrCl < 10 ml/min or HD:
1,200 mg IV q24h
[Administer dose after HD on dialysis day]
IV TO PO GUIDE [DIAMS HSgB]
IV Amoxycillin/Clavulanic Acid 1.2 g q8h
--> Tab Amoxicillin/ Clavulanate 625 mg TDS
Bioavailability:
Amoxicillin: 80%
Clavulanate: 30-98%
EXTENDED INFUSION GUIDE [DIAMS HSgB]
In-progress
SPECIAL MONITORING & PRECAUTION GUIDE [DIAMS HSgB]
In-progress
ALTERNATIVE DOSING (BLUE BOOK / HSgB DRUG LIST)
CHILD
less than 3 months: 30 mg/kg 12 hourly.
3 months - 12 years: 30 mg/kg 6 - 8 hourly.
ADULT:
1.2 g by IV or intermittent infusion 6 - 8 hourly