Abacavir Sulphate (ABC) 600 mg and Lamivudine (3TC) 300 mg tablet
Trade Name
Prescriber Category
:
:
Kivexa
A*
Department
Antimicrobial Restriction
:
:
ID
N/A
INDICATION (BLUE BOOK / UKK)
Antiretroviral combination therapy of HIV infection in adults and adolescents from 12 years of age with the following criteria:
-Patients unsuitable or failed other HAART treatment
-Patients who are at high risk of renal impairment
-Patients with osteoporosis or at high risk of bone loss
DOSING FOR ADULTS GUIDE [DIAMS HSgB]
ABC 600 mg/ 3TC 300 mg (1 tablet) PO daily
RENAL DOSE ADJUSTMENT IN ADULTS GUIDE [DIAMS HSgB]
Co-formulated tablet is not recommended in CrCl <5O.
CrCl <50 ml/min:
Use formulation for each component drug and adjust Lamivudine (3TC) dose according to recommendations for the individual drugs.
IV TO PO GUIDE [DIAMS HSgB]
N/A
EXTENDED INFUSION GUIDE [DIAMS HSgB]
In-progress
SPECIAL MONITORING & PRECAUTION GUIDE [DIAMS HSgB]
In-progress
ALTERNATIVE DOSING (BLUE BOOK / HSgB DRUG LIST)
ADULTS & ADOLESCENT (> 12 years of age):
Recommended dose is one tablet once daily.
Not to be used in adults or adolescents weigh less than 40kg.
CHILDREN : Not recommended