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Abacavir Sulphate (ABC) 300 mg Tab
Trade Name
Prescriber Category
:
:
Ziagen
A*
Department
Antimicrobial Restriction
:
:
ID
N/A
INDICATION (BLUE BOOK / UKK)
Antiretroviral combination therapy of HIV infection in adults and adolescents from 12 years of age.
i. Patients unsuitable or failed other HAART treatment
ii. Patients who have renal impairment (CrCl < 50ml/min) when Abacavir and Lamivudine fixed-dose combination is not recommended
DOSING FOR ADULTS GUIDE [DIAMS HSgB]
300 mg PO q12h
or
600 mg PO q24h
RENAL DOSE ADJUSTMENT IN ADULTS GUIDE [DIAMS HSgB]
No dosage adjustment required
IV TO PO GUIDE [DIAMS HSgB]
N/A
EXTENDED INFUSION GUIDE [DIAMS HSgB]
In-progress
SPECIAL MONITORING & PRECAUTION GUIDE [DIAMS HSgB]
In-progress
ALTERNATIVE DOSING (BLUE BOOK / HSgB DRUG LIST)
ADULT:
300 mg twice daily or 600 mg daily
CHILDREN:
i. Weighing 14 to <20 kg: one-half of a scored abacavir tablet twice daily
ii. Weighing ≥20 kg to <25 kg: one-half of a scored abacavir tablet in the morning and one whole tablet in the evening
iii. Weighing at least 25 kg: according to the adult dose
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